MOVIES:
Dumbo (the scene where his mother is cradling him in her trunk while she’s locked in the circus train car)
Ice Age (the part where the little baby’s parents are killed and the part where the mammoth has to give the baby up to the human tribe).
Wall-E (there are a few scenes where Wall-e thinks he’s lost Eve)
Chicken Run (the scene where they show a silhouette of one of the hens getting her head cut off). I didn’t think this movie was cute or funny at all.
My Sister’s Keeper (this was a 10 hankie movie).
Old Yeller (the scene where the boy ends up having to shoot his dog, because he has rabies)
The final episode of Harry Potter (when Harry collects Snape’s tears in the vial, while Snape is dying).
Star Trek The Wrath of Khan (when Spock is in that chamber dying and Kirk has his hand up to the glass, and then the scene where Spock’s coffin is being shot out into space while Amazing Grace is being played on a bagpipe).
Sex and the City movie (the scene where Carrie sees and realizes that Mr. Big has ditched her as she is getting out of the limo to marry him).
The Wizard of Oz (the scene where Dorothy has to say goodbye to the Scarecrow)
When Harry Met Sally (the scene where Meg Ryan finds out her longtime boyfriend is marrying someone else almost immediately after breaking up with her, and she says something like, “He wanted to get married, he just didn’t want to marry me.”)
Little Big Man (the scene where Dustin Hoffman wakes up with his Indian wife in their village and the U.S. army comes through and kills most of the women and children, including his wife).
Sense and Sensibility (the scene where Emma Thompson finds out that Hugh Grant has something important and very unexpected to tell her, and she starts sobbing uncrontrollably) Didn’t want to give the spoiler, because it is a crucial moment in the movie, that changes the course of everyone’s lives.
Shadowlands (the scene in which Debra Winger finally gets a shy Anthony Hopkins, who is playing the writer C.S. Lewis, into a romantic situation, and then he shyly admits that he has never been with a woman, even though he’s in his late 40’s. It was such a sweet, tender moment)
Butch Cassidy and the Sundance Kid (the scene at the end) Don’t want to add a spoiler those folks who haven’t seen it. If you haven’t seen it, you must!
Star Wars Episode IV (the scene where the main characters are walking down the aisle to get their medals. The music, the pageantry, the smiles on their faces, just everything about it was perfect!) You can see it Here
BOOK
The only one I can think of right now is “Standing in the Rainbow” by Fannie Flagg. This is the best book I have ever read.