Protection against obesity - How promising is nicotinamide riboside, a substance found in milk?

Wow! Intriguing. I would be very interested to see if high doses were OK and without side effects.

High dairy diets have been around for quite a while and studies show that women who consume high protein and fat via dairy lost fat and gained more muscle mass than women on similar exercise plans but low dairy. Google high dairy diet and you will get a couple of million hits.

I drink at least a pint of milk every day.
I also eat cheese and lots of yoghurt.
I am very skinny, despite having a diet high in fat. Maybe they’re on to something there, it would explain why despite me eating so much fatty food I fail to gain any weight.

@marinelife – It seems that mice consuming high doses were able to do this without side effect. But there are no studies about humans.

@rooeytoo – This is amazing. Google even suggests term completions containing weight loss. I wasn’t aware of this. Thanks! Maybe the reason for this effects now becomes more clear.

I think you chose the perfect Fluther name, @MilkyWay !

I find it ridiculous. And typical.
Why stop stuffing your face with fat when you have a nice pill you can swallow and then can continue with your gluttony?

@ragingloli – Because in the modern world many people are forced to sit in an office all day and in a train or car during long commutes, while at the same time our grocery stores offer more tasty stuff than kings and queens had 200 years ago. I agree that self discipline and a healthy life style is the better approach, but if such a pill can improve the health of people who keep failing doing this. Using your logic, people with high blood pressure should completely change their lives so they don’t have to swallow blood pressure medication. Is this practical? Very often high blood pressure is caused by our modern life style.

I will stick with eating sensibly and exercising regularly

Yes, and so do I. But in general, the human mind was optimized for starvation in the near future. In combination with genes that favor fat storage this can become a problem. There are also genes favoring addiction and lowering the capacity to resist urges for tasty food. If a pill can help millions of people who have trouble with food, why not use it? Exercise is very hard when people are very overweight and for obese people most forms of exercise become impossible. Not every obese person has access to a swimming pool. If the pill prevents an existing obesity from getting worse, doctors should consider prescribing them. And this leads us to another interesting discussion. If such a pill is safe I’m against selling it without a prescription. But that approach might become ineffective, because illegal drugs can be ordered over the Internet. Someone will sell the pill. Healthy people with normal weight might become tempted using it as well.

I do find this interesting. I have noticed how much easier it is for me to keep the weight off over the past 20 years of my adult life when I include more dairy in my diet. This doesn’t mean that I pig out on junk food on top of all the dairy that is included in my diet, but including dairy products, along with lean meat and veggies has worked better for me than just sticking with lean meats, fruits and veggies. A typical day for me would be a high fiber cereal with milk for breakfast, yogurt for a snack, cottage cheese and fruit for lunch, meat and salad for dinner and a small bowl of ice cream for dessert. It works for me.

I’ll let you know what I think when they come out with a supplement that can help with weight loss. That shouldn’t take more than, oh, say, a decade or two.

@mattbrowne Thank you :D

Could a comparison between vegetarians and vegans support the dairy diet effects?