At six weeks you probably would be seeing some effect. It’s time to talk to your psychiatrist and consider trying something else. The psychiatrist may urge you to try a little longer. But I would say that if you haven’t had any benefit in three months, then it won’t work for you.
Most likely you will have to try between three and fifteen different meds before you find one that works well with side effects you can tolerate. Medicine doesn’t know how to match up meds to people yet. They can’t do it based on diagnosis—they essentially try pretty much the same meds for all kinds of mental diagnoses, and they can’t do it based on individual biochemistry, yet. Hopefully, in the future, they will be more accurate. Meanwhile, it is a long, frustrating process to find the drug that helps alleviate depression.
Depression isn’t a moral failure, by the way. You can be as tough as a marine and still be unable to gain any control over depression. You can know every coping technique in the book and then some, and be unable to beat it. You can have therapy out the wazoo, and be unable to cope.
Sometimes meds can help. Sometimes you need electric shock therapy. Sometimes you need magnetic therapy. The last two will sometimes work in cases where meds can’t help, but magnetic therapy, even though effective, isn’t covered by insurance and it is very expensive. If it comes down to that, the University of Pennsylvania Hospital is where the therapy was pioneered and they know the most about it.
My point is don’t blame yourself for being unable to beat depression. In fact, you may find that you can’t beat depression until you give up fighting it. That was my experience, and the experience of many folks I know. It’s counter-intuitive, but I can explain it, if you like. Or link you to other places where I’ve written about it.
In any case, you have little control over the depression. Some, but not enough if it is as bad as it sounds like it is. You will need help. Therapy, exercise, eating right, getting good sleep, yoga, meditation, doing creative things, helping others, taking your meds, seeing a therapist, joining and participating in a depression support group: these are all things that help. It’s a laundry list and it may seem overwhelming at first, but one step at a time. One day at a time. (Wundayatta time). That’s how I managed to get my head above water. That’s how I managed to stay alive. If anything can work for you, that list will.