My Synvisc shots have been done in a series of three, each separated by a week. Six months later, another series.
Normally, there was occasionally some amount of pain in one or another knee depending upon the angle or placement of the needle (I guess) but basically tolerable and not both knees. Sometimes it was sore a bit the next day or so, but nothing alarmingly unbearable.
This last time, it wasn’t particularly painful in the office, but the next day, it was horrendous. I couldn’t walk without excruciating pain in BOTH knees and I immediately called the office (which I had never done in the 2–3 years prior).
I was convinced it must have been a bad batch of Synvisc or a severe allergic reaction and was really alarmed. I’m not the type to make mountains out of molehills, but this was also around the time that the news was just coming out about the tainted injectable steroid meds from that compounding Pharmacy which went all over certain parts of the country (Michigan was on the list of states with confirmed illness or deaths)
It was just so different from all the other times that I didn’t know what to think. Well, my Dr. reassured me it wasnt a bad batch of Synvisc and the usual advice about ice, etc etc.
Long story short, this lasted most of the week and it was The same story the next two times also. I haven’t developed any sudden allergy to eggs as I can eat them just fine so it’s the end of the line for me as far as the Synvisc is concerned,
It was really only about 20% successful anyway but I was willing to put up with the shots as long as it was basically bearable. But being out of commission for most of a week following each shot is just not worth it to me.
That’s not to say that this would ever happen with you, but at least if it does, you’ll know that a tainted batch is not the cause. (Synvisc comes straight from the manufacturer and is not being compounded by some hole in the wall unregulated Pharmacy owing its existence to a loophole in the FDA regulations.)