What is the right number of days to work from home?

I have been working from home sporadically, and recently have tired of the commute and office politics. I can increase the number of days working from home. My boss is really flexible and supportive. I feel working from home full time may be too isolating.

How many days a week do you think I should work from home and why?

What are some tips for working at home for extended periods? I have a great home office set up already.