Is this the final nail in the coffin for anti-vaccers?

No. They weren’t reasoned into the position, they won’t be reasoned out.

No. What’s to stop them from saying the vaccine in combination with this predisposition makes it worse, or brings on the autism, or however they want to think of it.

It wasn’t the final nail in the coffin the last time I heard this as a new finding, which was maybe 6–8 years ago. There is no proof for anti-vaxxers’ claims; they hold the idea of an autism-vaccine link as a belief. No amount of evidence is going to convince them.

Of course not. Vaccines start at 2 months of age

No. They have the alternate facts on their side.

I changed my mind. I have autism in my family so we didn’t want to risk it. About 4 years ago (they were 12y and 6y old) I thought that they were both normal so had them given the MMR. They are both still normal.

South Africa has launched a major clinical trial of an experimental vaccine against the AIDS virus, which scientists hope could be the “final nail in the coffin” for the disease.

More than 30 years of efforts to develop an effective vaccine for HIV have not borne fruit, but for the first time since the virus was identified in 1983, scientists said on Wednesday they think they have found a promising candidate.

The new study, known as HVTN 702, will involve more than 5,400 sexually active men and women aged 18–35 in 15 areas around South Africa over four years.

What makes you think their argument was ever based on the available evidence?

No, they will probably say that it is just evidence of an elitist scientist conspiracy.