Is it safe to crush pills and dissolve them in water?

It’s ok for some meds and not for others. You can always ask the pharmacist or call the drug company. A basic rule is don’t open up capsules, but even with capsules it’s sometimes ok.

Crushing an excedrin is fine, just be sure to eat with it a little and plenty of water.

There is liquid Tylenol and liquid ibuprofen so you can make liquid excedrin yourself. Just read how many milligrams in a dose and measure it out and drink a coffee or Coke with it. Excedrin actually has aspirin not ibuprofen I think, so if you want exactly the drug in excedrin you can buy chewable aspirin. It comes in many flavors usually in the children’s/heart disease dose. You just take three or four of them. Again, just look at the ingredients.

Even with chewable aspirin be sure to drink plenty of water. Having a little food wth it is good too, even if it’s just a cracker.

Forgot to add that’s all over the counter. Just look at all the children’s meds. You won’t be drinking a ton of it. Probably, the dose you need is one measuring teaspoon of Tylenol. Check it. I don’t know the measurements by heart.

Mucinex says never to chew it. I would also assume that also means don’t crush it before taking it.

Depends greatly on the substance. I don’t know about Excedrin specifically. An example where this wouldn’t be okay is meds that have an entoric coating that specifically makes sure they don’t dissolve until they reach the colon, so crushing them could make them dangerous or ineffective.

^^Partially right. Usually, the coating is to protect from the drug dissolving in the stomach, and usually it starts working in the small intestines, but I don’t doubt some are designed specifically for the colon, I don’t know the whole gamut. Still, your point goes to exactly why capsules especially people should use great caution, and that uncoated pills you can pretty safely bet it’s fine to mash it up or dissolve it, just need to make sure it’s ok with food if you mash it in food.

Some tablets are coated just for easier swallowing, not so much that avoiding the stomach avid is important, but for some drugs the efficacy goes way down if it is in stomach avid. Some drugs the coating is to protect the stomach. Two different things.

Always best to check with the pharmacy about a specific drug.

As others said, it is okay for some medications but not all medications. For example, you never want to crush any kind of time released/extended release medication. These are formulated to dissolve over time and slowly release the active ingredient of the medication into your system. If you crush those medication, you get all of the active ingredient at once instead of over time as it is intended.

Your best bet is to call a doctor or pharmacist to be sure if you ever have a doubt.