How do I make programs think there is no proxy?

I don’t know the specifics, but you may try running your software through an emulated LAN connection. I know that there are programs available that allow you to simulate a LAN. If you can trick the program into believing that it is connecting to the internet through the LAN (think connection sharing), then you may be able to fool it into thinking that it is running on a direct connection.

Do you follow?

What kind of computer / operating system is this? It would be too much to answer for me to cover every platform under the sun.

I need it to work on a computer running Windows Server 2003 and/or Windows XP.

Do you have access to a computer outside the campus network? Can it run a VPN server? OpenVPN is a great option here.

Is it a socks proxy? http proxy? what sort of proxy?

I think that skord is getting to the heart of this matter with his VPN answers. You basically have to connect to a different network to do what you are doing. VPN will let you do that.

I think tat you may just have to forgo your idea about whatever it is you are doing because getting around a proxy if the network won’t let you is going to be a large hassle. It may be time to redesign and save yourself some major headache time.