General Question

trailsillustrated's avatar

Has anyone tried "amberen"? Know where to get it?

Asked by trailsillustrated (16804points) July 21st, 2009

I want to try it but don’t want to get roped into an autoship thing. Anybody know where I can buy it without having my credit card billed for auto shipments?

Observing members: 0 Composing members: 0

4 Answers

shilolo's avatar

You should be very wary of this. There have been no clinical trials in the USA or Europe of this product. The one clinical trial I could find was from Russia, and essentially relied on questionnaires to determine subjective responses in 50 women (versus 20 control subjects) 3 weeks after treatment. There was also animal data in the study, which I reviewed and in essence was useless. The data is so bad in both the animal and human studies as to indicate no effect of amberen. Of course, you can feel free to try whatever you want, but the data for its effectiveness are scant at best.

NicoleLA's avatar

Shilolo, I became very intrigued with this because you stated there was nothing credible about the trials. Now, I am totally confused. I went to the same link you provided and on page 6 there is a section called Clinical Observations, that actually lists methods used during the clinical trials: “Kupperman Menopause Index, gynecological check-up’s, psychological evaluations, Spielberger-Hanin Anxiety Inventory, electrocardiography, ultrascanning of the uterus and uterine appendages and lab analyses of blood and urine samples.” Sounds pretty thorough to me!!! So, I don’t know how you concluded that it was based on questionnaires only… I actually read the whole thing and it’s very convincing (the parts I could understand, haha!), including the results they got from animal studies. Pretty fascinating… Shilolo, you should read some stuff women are posting online – a lot of incredible individual experiences. I got most of my questions answered. Oh, also, on Amberen’s website they state that it’s “against their policy” to bill your credit card without your knowledge. That’s important to me, too, because I actually had to close the card once, because I couldn’t get rid of some nuisance charges! Good luck!

trailsillustrated's avatar

I asked this months ago, but in case you are interested I did order it, not from their website, it works pretty well. I get it from apple health store on the net, no auto ship. it’s fine. also I just bought some bio identical progesterone cream. I’m trying that,too.

shilolo's avatar

@NicoleLA Using big sounding words and studies doesn’t mean that the actual data is meaningful. Did you look at the data in the paper? There is essentially no statistically significant benefit of the treatment versus placebo. Almost all the women who took something, placebo or drug, benefited from treatment (this is classic for a placebo effect), but the authors highlight only that those taking the amberen benefited (even though placebo treated women benefited too). As for the animal study, they started with 42 mice and eventually had 6 groups. Assuming they divided them equally (they don’t say), that means 7 mice per group. There isn’t enough power in such small sized groups (and the mice were outbred to boot) to identify meaningful differences. I would also question why this was published in a random Russian journal and not a more reputable journal? Finally, regarding what women are posting online, I’ll pass. Anecdotes are meaningless to me (I’m a scientist, if you haven’t figured that out already.)

Answer this question

Login

or

Join

to answer.

This question is in the General Section. Responses must be helpful and on-topic.

Your answer will be saved while you login or join.

Have a question? Ask Fluther!

What do you know more about?
or
Knowledge Networking @ Fluther