What is a great movie or book in which a character suddenly and mysteriously Disappears?

Happy Days. Chuck cunningham mysteriously disappears without any explanation. Spooooky! :)

Series of Unfortunate Events. There are many disappearances in that book.

The Lady Vanishes Hitchcock.

There was a Star Trek TNG episode where the whole crew disappeared one by one. I have no idea how you can find it.

Laura 1944, Dana Andrews, Gene Tierney. Ottto Preminger movie. Cast of many.

Oooh @PandoraBoxx! Great One! I love that movie!

Without a Trace, tv show- happens every episode.

hee hee

Eddie and the Cruisers.

shantaram. best book ever

Psycho.
The Stand. (mother Abigale)

TV shows like “Without a Trace” and “The Forgotten”. Also, check out the Kathy Reichs novels. I know they’re crime novels.

Put the title “Vanished” into Amazon’s book search and you’ll find an assortment of them.

Letters from the Inside is a fantastic piece of YA literature that fits the bill. I read it probably in sixth or seventh grade and it has stuck with me since then. If you’re an adult, don’t let the fact that it is YA throw you off—it is still very good and you can always think of it this way: a YA novel, when read by an adult, will last about as long as a movie.