What would happen if a set of dogs from two different litters were to breed together?

Yes. There are reasons why you should never do this. Birth defects etc, God forbid. Why would anyone wish suffering on innocent wee puppies like that.Please don’t take the risk.

Apart from everything else, there are already too many puppies without homes in the world and not enough homes to go round for the wee dogs and cats already in the world.
hugs honey xx

Probably nothing. When breeders are trying to establish a breed (or preserve some genetic mutation, like devon rex and scottish fold cats), they intentionally inbreed over several generations.

When was the breeding? If very recently, go ahead and have the bitch spayed. The surgery is longer and has a slightly higher risk for in-heat and pregnant dogs, but it can certainly be done.

If not, have the puppies checked for cleft palates and other issues when they’re born, and in the meantime, have the male castrated. As soon as the puppies are weaned, have the bitch spayed. Make sure that the homes that you place the puppies in sign a contract stating that they will spay and neuter the offspring.

You will find that one or two of the resultant puppies is/are completely insane. Just like the English royalty of olden days.

Damnit! @syz always gets to these questions before I do! I second @syz

@davidbetterman what do you mean like the olden days lol :-)
hugs xx
ps: thanks for the “English royalty” they’re bog all to do with us, we’re just forced to pay for them.

I see you mentioned Yorkies. They carry a genetic trait for dwarfism. It’s fairly prevalent and should it be present in either of the parents or the offspring are carrying it than interbreeding them could make that anomaly become present in subsequent offspring. Some people are breeding purposefully for this and calling the Yorkies “teacups”. In reality they are poor specimens that suffer pretty severe gastrointestinal problems. You may or may not see this anomaly in the litters that occur from this current round of breeding.